

µpattern MecaChips®
CONTROL YOUR MECHANICAL CELL ENVIRONMENT
AT THE MICROMETER SCALE
by Cell&Soft

Mechano-mimetic cell culture: textured rigidity
In vivo tissues are soft, elastic and mechanically textured. Living tissues rigidity properties present microscale variations that can play a crucial role in cell response (in a same tissue, rigidity varies from Pa/mm to kPa/μm).. Relying on unique patented technologies and know-how derived from the microelectronic field, the mechanical properties of Mecachips® matrices can be finely tuned up to the μm scale to replicate such variations.
DESCRIPTION
MecaChips® soft and micropatterned culture plates are new and physiological solutions for in vitro cell culture, that mimic the mechanical cell environment, all while giving you the chance to control it at the micrometer scale.
APPLICATIONS
AREAS
Basic research, stem cells, oncology, neurology, cardiology.
TOOLS
Adhesion, cell shape standardization, cell confinement, cell migration.
CHARACTERISTICS
BENEFITS
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Robust & reliable
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Ready & easy to use
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Scalable to screening workflow (no topography)
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No biological risk (synthetic matrix)
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Glass bottom: ideal for microscopy
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Stiffness and coating are decoupled
STORAGE
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Temperature: +4°C
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Shelf life: 3 months
SHAPES*
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Subcellular to cellular scale (1 - 100 μm): geometrics patterns (dots, triangles, stripes)
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Tissue scale (Pa/mm to kPa/μm): steps, gradients
*Custom patterns upon request
CUSTOMIZATION
CHOOSE YOUR STIFFNESS
Stiffness according to the organ of interest:
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1 kPa (breast)
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3 kPa (liver)
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3,5 kPa (pancreas)
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4 kPa (lung)
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5 kPa (artery | skin)
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6 kPa (brain)
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8 kPa (spleen)
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9 kPa (kidney)
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10 kPa (heart)
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>25 kPa (cartilage)
CHOOSE YOUR COATING
Culture dishes and plates are pre-coated with ECM protein or synthetic amino acid.
Culture dedicated surface chemistry:
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Vitronectin (human; recombinant truncated)
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Fibronectin (human; plasma)
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Collagen I (rat; tail)
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Laminin (mouse; EHC sarcoma)
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Poly-Ornithine | Laminin
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Poly-Ornithine
UNIQUE FORMAT
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PD35
PRODUCT SHEET
Download product sheet here.
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MecaChips®
Discover our physiological solutions for in vitro cell culture

MecaTract
Polyacrylamide gel with fluorescent beads dispersed inside for Traction Force Microscopy.
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