To be representative, in vitro cell devices should selectively provide culture conditions as close as possible to the mechanical microenvironment of targeted tissues.
Cell&Soft culture plates offer mechanical features as close as possible to those found in vivo in animal or human tissues. In vivo, cells lay in soft tissues with distinct physical properties. Rigidity plays a major role in a myriad of cellular mechanisms, such as carcinogenesis and metastasis formation, as well as stem cells differentiation and drug effectiveness. Mecachips™ soft and flat matrices are new and physiological solutions for in vitro cell culture. They mimic the soft mechanical features of all human or animal tissues, thus preserving the cells in vivo characteristics.
Basic research, stem cells, oncology, neurology, cardiology, compatible with HCS/HTS platforms.
Cell biology, molecular biology, biochemistry.
Robust & reliable
Scalable to screening workflow (no topography)
No biological risk (synthetic matrix)
Glass bottom: ideal for microscopy
Stiffness and coating are decoupled
Compatible with standard analysis
Shelf life: 3 months
Choose yout organ of interest
MECHANO-MIMETIC CELL CULTURE
Choose your coating
CULTURE DEDICATED SURFACE CHEMISTRY
Culture dishes and plates are pre-coated with ECM protein or synthetic amino acid:
Fibronectin (human, recombinant truncated)
Collagen I (rat, tail)
Laminin (mouse, EHS sarcoma)
Choose your format
*P384 upon request