Mechano-mimetic cell culture.
Uniform rigidity.
In vivo, cells lay in soft tissues with distinct physical properties. Rigidity plays a major role in a myriad of cellular mechanisms, such as carcinogenesis and metastasis formation, as well as stem cells differentiation and drug effectiveness. To be representative, in vitro cell devices should selectively provide culture conditions as close as possible to the mechanical microenvironment of targeted tissues.