MecaChips®

 

SOFT CULTURE PLATES FOR PLEASED CELLS

by Cell&Soft

P96.png

Mechano-mimetic cell culture.
Uniform rigidity.

In vivo, cells lay in soft tissues with distinct physical properties. Rigidity plays a major role in a myriad of cellular mechanisms, such as carcinogenesis and metastasis formation, as well as stem cells differentiation and drug effectiveness. To be representative, in vitro cell devices should selectively provide culture conditions as close as possible to the mechanical microenvironment of targeted tissues. 

DESCRIPTION

Cell&Soft culture plates offer mechanical features as close as possible to those found in vivo in animal or human tissues. Mecachips® soft and flat matrices are new and physiological solutions for in vitro cell culture. They mimic the soft mechanical features of all human or animal tissues, thus preserving the cells in vivo characteristics.

APPLICATIONS

AREAS | Basic research, stem cells, oncology, neurology, cardiology, compatible with HCS/HTS platforms.

TOOLS | Cell biology, molecular biology, biochemistry.

CHARACTERISTICS

BENEFITS | Relevant, robust, reliable, plug & play, compliant, disruptive, scalable to screening workflow (no topography), no biological risk (synthetic matrix), glass bottom: ideal for microscopy, stiffness and coating are decoupled, compatible with standard analysis.

STORAGE | Temperature: +4°C. Shelf life: 3 months.

CUSTOMIZATION

1

CHOOSE YOUR STIFFNESS

Stiffness according to the organ of interest:

1 kPa_Breast.png

Breast

1 kPa

3 kPa_Liver.png

Liver

3 kPa

3,5 kPa_Pancreas.png

Pancreas

3 kPa

4 kPa_Lung.png

Lung

4 kPa

5 kPa_Arteries.png

Artery

5 kPa

5 kPa_Skin.png

Skin

5 kPa

6 kPa_Brain.png

Brain

6 kPa

8 kPa_Spleen.png

Spleen

8 kPa

9 kPa_Kidney.png

Kidney

9 kPa

10 kPa_Heart.png

Heart

10 kPa

25 kPa_Cartilage.png

Cartilage >25 kPa

*Specifics stiffnesses on request

Culture dishes and plates are pre-coated with ECM protein or synthetic amino acid. Culture dedicated surface chemistry:

2

CHOOSE YOUR COATING

Vitronectin

Human; recombinant truncated

Human; plasma

Fibronectin

Collagen I

Rat; tail

Laminin

Mouse; EHC sarcoma

Poly-Ornithine | Laminin

Poly-Ornithine

Standards formats*:

BP35.png

PD35

P12.png

P12

p48.png

P48

P6.png

P6

P24.png

P24

P96.png

P96

*p384 on request

3

CHOOSE YOUR FORMAT

 

See other products...

Soft and rigidity micropatterned culture plates.
Polyacrylamide gel with fluorescent beads dispersed inside for Traction Force Microscopy.