Mechano-mimetic cell culture.
In vivo, cells lay in soft tissues with distinct physical properties. Rigidity plays a major role in a myriad of cellular mechanisms, such as carcinogenesis and metastasis formation, as well as stem cells differentiation and drug effectiveness. To be representative, in vitro cell devices should selectively provide culture conditions as close as possible to the mechanical microenvironment of targeted tissues.
Cell&Soft culture plates offer mechanical features as close as possible to those found in vivo in animal or human tissues. Mecachips® soft and flat matrices are new and physiological solutions for in vitro cell culture. They mimic the soft mechanical features of all human or animal tissues, thus preserving the cells in vivo characteristics.
AREAS | Basic research, stem cells, oncology, neurology, cardiology, compatible with HCS/HTS platforms.
TOOLS | Cell biology, molecular biology, biochemistry.
BENEFITS | Relevant, robust, reliable, plug & play, compliant, disruptive, scalable to screening workflow (no topography), no biological risk (synthetic matrix), glass bottom: ideal for microscopy, stiffness and coating are decoupled, compatible with standard analysis.
STORAGE | Temperature: +4°C. Shelf life: 3 months.
CHOOSE YOUR STIFFNESS
Stiffness according to the organ of interest:
Cartilage >25 kPa
*Specifics stiffnesses on request
Culture dishes and plates are pre-coated with ECM protein or synthetic amino acid. Culture dedicated surface chemistry:
CHOOSE YOUR COATING
Human; recombinant truncated
Mouse; EHC sarcoma
Poly-Ornithine | Laminin
*p384 on request
CHOOSE YOUR FORMAT